File Name: quality in laboratory hemostasis and thrombosis .zip
Show more about author. The essential elements of a quality program, specifically internal quality control IQC and external quality assurance EQA , should be applied to each laboratory assay performed in order to ensure test result accuracy and precision. The coagulation laboratory plays an important role in the diagnosis and treatment of individuals with bleeding or clotting i.
Hemostasis is a delicate, dynamic and intricate system, in which pro- and anti-coagulant forces cooperate for either maintaining blood fluidity under normal conditions, or else will prompt blood clot generation to limit the bleeding when the integrity of blood vessels is jeopardized. Excessive prevalence of anticoagulant forces leads to hemorrhage, whereas excessive activation of procoagulant forces triggers excessive coagulation and thrombosis. The hemostasis laboratory performs a variety of first, second and third line tests, and plays a pivotal role in diagnostic and monitoring of most hemostasis disturbances. Since the leading targets of Clinical Chemistry and Laboratory Medicine include promotion of progress in fundamental and applied research, along with publication of guidelines and recommendations in laboratory diagnostics, this journal is an ideal source of information on current developments in the laboratory technology of hemostasis, and this article is aimed to celebrate some of the most important and popular articles ever published by the journal in the filed of laboratory hemostasis.
Key words:. A shared statement of ethical principles for those who shape and give healthcare. A working draft from the Tavistock Group. Ann Int Med ; 2 Sandrick K. A unifying force.
Next Quality in Laboratory Hemostasis and Thrombosis. Quality in hemostasis and thrombosis--part III. Quality in laboratory hemostasis and thrombosis second edition edited by steve kitchen, clinical scientist, sheffield haemophilia and thrombosis centre. The coagulation laboratory offers a wide variety of testing to aid in the diagnosis the quality of test General quality planning in the hemostasis laboratory John D. Hemostasis test validation, performance, and reference intervals international recommendations and guidelines Richard A.
Olson , F. Professor Preston has been a co-author on more than publications in peer reviewed journals in the field of hemostasisand thrombosis. He is the head scientist at theSheffield Haemostasis and Thrombosis Centre. He has 25 yearsexperience in the field of laboratory testing in haemostasis with along standing interest in standardisation and has been involved indrawing up guidelines for a number of National and Internationalbodies in the field. John D. He has had acontinuing interest in haemostasis and thrombosis that has spannedhis career of more than 30 years. This committee a the largest externalquality assurance program in haemostasis in North America.
Quality Assurance in the laboratory ensures that the result a laboratory generates and reports is accurate, precise and specific. External quality assurance EQA is an important component of the total quality assurance program of a clinical haemostasis laboratory. The same test, performed on the same specimen, should give the same answer wherever and by whoever it is carried out.
The premise of this concept was to improve all phases of laboratory testing, specifically pre-analytical, analytical and post-analytical processes. Hemostasis testing is particularly sensitive to pre-analytical issues, including sample collection, handling, transportation, processing and storage 2. Each of these steps needs to be addressed and controlled locally with proper, consistent institutional procedures and protocols to minimize pre-analytical errors. Quality assurance measures specific for the analytical phase of hemostasis testing occurs: I during the initial test evaluation method validation of test performance ; II as part of periodic quality control QC daily or as required QC performance ; and III during episodic assessment using external quality assurance EQA, also commonly referred as Proficiency Testing. According to the College of American Pathologists CAP , the benefits of participation in an EQA program include improving laboratory practice, characterizing local test performance over site specific and multiple platforms, identifying potential test interferences e.
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Metrics details. Ensuring quality has become a daily requirement in laboratories.
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